Question 1

Purified protein from Bordetella pertussis is used in a(n)

Accepted Answer

A)   conjugated vaccine.
B)   attenuated whole- agent vaccine.
C)   toxoid vaccine.
D)   nucleic acid vaccine.
E)   subunit vaccine.F) A) and B)
G) A) and C) E

Question 2

Toxoid vaccines, such as the vaccines against diphtheria and tetanus, elicit a(n)

Accepted Answer

A)   immune complex.
B)   antibody response against these bacterial toxins.
C)   TC cell response.
D)   dendritic cell proliferation.
E)   antibody response against gram- positive bacteria.F) C) and E)
G) A) and B)

Question 3

Haemophilus capsule polysaccharide plus diphtheria toxoid is a(n)

Accepted Answer

A)   inactivated whole- agent vaccine.
B)   attenuated whole- agent vaccine.
C)   conjugated vaccine.
D)   subunit vaccine.
E)   toxoid vaccine.F) B) and E)
G) A) and B)

Question 4

All of the following are generally used in vaccines EXCEPT

Accepted Answer

A)   parts of bacterial cells.
B)   toxoids.
C)   inactivated viruses.
D)   antibodies.
E)   live, attenuated bacteria.F) D) and E)
G) A) and D)

Question 5

What type of vaccine involves host synthesis of viral antigens?

Accepted Answer

A)   subunit vaccine
B)   toxoid vaccine
C)   nucleic acid vaccine
D)   attenuated whole- agent vaccine
E)   conjugated vaccineF) A) and D)
G) A) and E)

Question 6

The home pregnancy test kit is an example of a direct ELISA.

Accepted Answer

A) True 
 B)False

Question 7

A positive complement- fixation test in indicated by the lysis of the sheep red blood cells added in the indicator phase of the test.

Accepted Answer

A) True 
 B)False

Question 8

The following steps are used to produce monoclonal antibodies. What is the fourth step?

Accepted Answer

A)   Culture the hybridoma.
B)   Isolate antibody- producing B cells.
C)   A B cell is activated to produce antibodies.
D)   Fuse a B cell to a myeloma cell.
E)   Vaccinate a mouse.F) All of the above
G) A) and E)

Question 9

Table 18.1
 
-In Table 18.1, who probably has the disease?

Accepted Answer

A)   Patients C and D
B)   Patients A and C
C)   Patients A and D
D)   Patients A and B
E)   Patients B and CF) A) and B)
G) C) and D)

Question 10

In an immunodiffusion test to diagnose histoplasmosis, a patient's serum is placed in a well in an agar plate. In a positive test, a line forms as the serum diffuses from the well and meets material diffusing from a second well. What type of test is this?

Accepted Answer

A)   an ELISA test
B)   an agglutination reaction
C)   a complement- fixation test
D)   a direct test
E)   a precipitation reactionF) B) and E)
G) A) and B) E

Question 11

A test used to identify Streptococcus pyogenes in a patient's throat swab is the

Accepted Answer

A)   hemagglutination test.
B)   hemagglutination- inhibition test.
C)   indirect ELISA test.
D)   direct fluorescent- antibody test.
E)   indirect fluorescent- antibody test.F) A) and B)
G) A) and C)

Question 12

A test used to detect anti- Rickettsia antibodies in a patient's serum is the

Accepted Answer

A)   indirect fluorescent- antibody test.
B)   direct fluorescent- antibody test.C) A) and B)
D) undefined

Question 13

A DNA plasmid encoding a protein antigen from West Nile virus is injected into muscle cells of a horse. This is an example of a(n)

Accepted Answer

A)   subunit vaccine.
B)   attenuated whole- agent vaccine.
C)   conjugated vaccine.
D)   live whole- agent vaccine.
E)   nucleic acid vaccine.F) C) and E)
G) None of the above

Question 14

Inactivated tetanus toxin is a(n)

Accepted Answer

A)   conjugated vaccine.
B)   subunit vaccine.
C)   nucleic acid vaccine.
D)   inactivated whole- agent vaccine.
E)   toxoid vaccine.F) C) and D)
G) A) and E)

Question 15

Western blotting uses antibodies to detect specific proteins in a mixture of proteins.

Accepted Answer

A) True 
 B)False

Question 16

An injection of "naked" DNA into muscle cells to induce an immune response against the proteins encoded by the DNA is an example of a subunit vaccine.

Accepted Answer

A) True 
 B)False

Question 17

In an agglutination test, eight serial dilutions to determine antibody titer were set up. Tube #1 contained a 1:2 dilution; tube #2, a 1:4, etc. If tube #6 is the last tube showing agglutination, what is the antibody titer?

Accepted Answer

A)   6
B)   64
C)   1:6
D)   1:32
E)   32F) A) and E)
G) C) and D)

Question 18

A vaccine against HIV proteins made by vaccinia virus is a(n)

Accepted Answer

A)   conjugated vaccine.
B)   subunit vaccine.
C)   nucleic acid vaccine.
D)   inactivated whole- agent vaccine.
E)   toxoid vaccine.F) A) and C)
G) B) and D)

Question 19

Which of the following is NOT an advantage of live attenuated vaccine agents?

Accepted Answer

A)   They require few or no booster immunizations.
B)   They stimulate by cell- mediated and humoral immune responses.
C)   They occasionally revert to virulent forms.
D)   They elicit lifelong immunity.
E)   The immune response generated by the vaccine closely mimics a real infection.F) A) and B)
G) A) and E) C

Question 20

A hybridoma results from the fusion of a(an)

Accepted Answer

A)   antigen with a B cell.
B)   myeloma cell with a virus.
C)   B cell with a myeloma cell.
D)   B cell with a T cell.
E)   antigen with an antibody.F) B) and E)
G) D) and E)

Exam 18: Practical Applications of Immunology

Purified protein from Bordetella pertussis is used in a(n)

Correct AnswerverifiedE

Toxoid vaccines, such as the vaccines against diphtheria and tetanus, elicit a(n)

Correct AnswerverifiedShow Answer

Haemophilus capsule polysaccharide plus diphtheria toxoid is a(n)

Correct AnswerverifiedShow Answer

All of the following are generally used in vaccines EXCEPT

Correct AnswerverifiedShow Answer

What type of vaccine involves host synthesis of viral antigens?

Correct AnswerverifiedShow Answer

The home pregnancy test kit is an example of a direct ELISA.

Correct AnswerverifiedShow Answer

A positive complement- fixation test in indicated by the lysis of the sheep red blood cells added in the indicator phase of the test.

Correct AnswerverifiedShow Answer

The following steps are used to produce monoclonal antibodies. What is the fourth step?

Correct AnswerverifiedShow Answer

Table 18.1 -In Table 18.1, who probably has the disease?

Correct AnswerverifiedShow Answer

In an immunodiffusion test to diagnose histoplasmosis, a patient's serum is placed in a well in an agar plate. In a positive test, a line forms as the serum diffuses from the well and meets material diffusing from a second well. What type of test is this?

Correct AnswerverifiedE

A test used to identify Streptococcus pyogenes in a patient's throat swab is the

Correct AnswerverifiedShow Answer

A test used to detect anti- Rickettsia antibodies in a patient's serum is the

Correct AnswerverifiedShow Answer

A DNA plasmid encoding a protein antigen from West Nile virus is injected into muscle cells of a horse. This is an example of a(n)

Correct AnswerverifiedShow Answer

Inactivated tetanus toxin is a(n)

Correct AnswerverifiedShow Answer

Western blotting uses antibodies to detect specific proteins in a mixture of proteins.

Correct AnswerverifiedShow Answer

An injection of "naked" DNA into muscle cells to induce an immune response against the proteins encoded by the DNA is an example of a subunit vaccine.

Correct AnswerverifiedShow Answer

In an agglutination test, eight serial dilutions to determine antibody titer were set up. Tube #1 contained a 1:2 dilution; tube #2, a 1:4, etc. If tube #6 is the last tube showing agglutination, what is the antibody titer?

Correct AnswerverifiedShow Answer

A vaccine against HIV proteins made by vaccinia virus is a(n)

Correct AnswerverifiedShow Answer

Which of the following is NOT an advantage of live attenuated vaccine agents?

Correct AnswerverifiedC

A hybridoma results from the fusion of a(an)

Correct AnswerverifiedShow Answer

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E

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E

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C

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